Human Beta Amyloid 1-42 Antibody Pair(ARA954/ARA834)

Datasheet

MSDS

Human Beta Amyloid 1-42 Antibody Pair(ARA954/ARA834)

Key features and details

Target: Beta Amyloid 1-42
Host: Mouse
Reactivity: Human
Clonality: Monoclonal
Application: Sandwich ELISA
Storage: -20°C

Brand:

CAT.NO. : ARA6834

US$ Please choose

Size:

pair(100μg*2)

Trail, Bulk size or Custom requests Please contact us

Product Details

Background

Beta amyloid is a 40-43 amino acid peptide cleaved from amyloid precursor protein by a protease, gamma-secretase. Beta Amyloid (1-40) (Amyloid beta 40 or Abeta 40) together with beta Amyloid (1-42) (Amyloid beta 42 or Abeta 42) are two major C-terminal variants of the amyloid beta protein, constituting the majority of amyloid beta proteins. Both the Amyloid beta 40 and Amyloid beta 42 alloforms are major components of the extracellular plaques found in Alzheimer's disease brain tissue.

Content

To ensure optimal assay performance, AREX recommends conducting reagent titration tailored to each testing system for optimal detection results.

Products include	Catalog No.
Beta Amyloid Mouse Monoclonal Antibody(ARA954)	ARA6798
Beta Amyloid 1-42 Mouse Monoclonal Antibody(ARA834)	ARA6655
Human beta Amyloid 1-42 peptide	AXP6611

*Results are sample-specific. Please refer to your local assay conditions and test parameters for reference.

Overview

Antibody Pair Specificity	Beta Amyloid 1-42
Species Reactivity	Human
Protein Standard	Human beta Amyloid 1-42 polypeptide [AXP6611]
Target Antigen	Protein name: amyloid beta precursor protein; Gene name: APP; UniProt Accession: P05067; Organism: Homo sapiens (Human)

*AREX continuously optimizes our products. Webpage content may not reflect the latest updates. For inquiries, please contact info@arexbio.com or your local distributor.
*Clone Number, Reactivity, Source/Host and Clonality can be found in the product name and Key Features section above.

Data

Microtiter wells were coated with ARA954 at 2 µg/mL as the capture antibody. Human beta Amyloid 1-42 peptide (Cat #: AXP6611) was used as the antigen. 700 ng/mL biotin conjugated Beta Amyloid 1-42 Antibody [ARA834] was used as the detection antibody. Result: ARA954 and ARA834 can be used as a matched antibody pair to detect and quantify the concentration of Human Beta Amyloid 1-42 with high specificity.

Storage

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

Note

For Research Use Only. Not for diagnostic, therapeutics, prophylactic or in vivo use.

FAQs

What are the main types of research antibodies and how do they differ?

Research antibodies are mainly divided into monoclonal antibodies and polyclonal antibodies. Monoclonal antibodies typically offer higher specificity and better batch-to-batch consistency, while polyclonal antibodies often provide stronger affinity but may show more variation between batches. The choice depends on your specific experimental needs.

How can I tell if a research antibody is suitable for my experiment?

It is recommended to carefully review the product datasheet for validated applications, species reactivity, recommended dilutions, and published references. For new antibodies, performing a small-scale validation with positive control samples is usually helpful.

Can improper storage of research antibodies affect experimental results?

Yes. Antibodies are sensitive to temperature, repeated freeze-thaw cycles, and contamination. Improper storage may lead to reduced activity, increased background, or weaker signals. It is best to follow the storage instructions provided in the product datasheet.

Why doesn’t the recommended dilution in the datasheet work well in my experiment?

The recommended dilution is based on the supplier’s test conditions. Factors such as sample type, fixation method, and detection system in your lab can influence the optimal working concentration. Performing a dilution series optimization in your own system is often necessary.

What precautions should I take when using a newly purchased research antibody for the first time?

It is advisable to briefly centrifuge the antibody (especially concentrated or lyophilized ones), then perform a small-scale pilot experiment using the recommended conditions. Recording the batch number and usage date is also helpful for future tracking.

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