SYN1-Specific Rabbit Monoclonal Antibody(ARA630)
MSDS 
Key features and details
- Target:
- Host:
- Reactivity:
- Clonality:
- Applications:
- Conjugation:
- Storage:
-
Brand:
CAT.NO. : ARA6333
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Product Details
Background
SYN1, also named Brain protein 4.1, belongs to the synapsin family. SYN1 is a neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level. Defects in SYN1 are a cause of epilepsy X-linked with variable learning disabilities and behavior disorders (XELBD).
Application
|
Application |
Dilution Ratio |
|
WB |
1:5000 - 1:50000 |
|
IF/ICC |
|
Overview
|
Antibody Type |
Recombinant Rabbit monoclonal Antibody |
|
Immunogen |
Recombinant protein within human CRBN aa 1-442 / 442. |
|
Species Reactivity |
Human, Mouse, Rat |
|
Applications |
WB, IHC, IF, IP |
|
Predicted Molecular Weight |
51 kDa |
|
Positive Control |
HEK-293 cell lysate, A375 cell lysate, A549 cell lysate, HeLa cell lysate, SH-SY5Y cell lysate, NIH/3T3 cell lysate, MCF7 cell lysate, mouse brain tissue lysate, rat testis tissue lysate, human testis tissue, human brain tissue. |
|
Conjugate |
Unconjugated |
|
Form |
Liquid |
|
Storage Buffer |
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide. |
|
Isotype |
IgG |
|
Purification Method |
Protein A affinity purified. |
Data
Various lysates were subjected to SDS PAGE followed by western blot with SYN1-Specific Rabbit Monoclonal Antibody(ARA630) at dilution of 1:10000 incubated at room temperature for 1.5 hours.
Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded rat brain tissue using SYN1-Specific Rabbit Monoclonal Antibody(ARA630) at dilution of 1:200 and AREX® Flour 488-Conjugated Goat Anti-Rabbit IgG(H+L) . Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Note
For Research Use Only. Not for use in diagnostic procedures.
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