EGFR Rabbit Monoclonal Antibody(ARA731)
Key features and details
- Target:
- Clone ID:
- Host:
- Clone Type:
- Purity:
- Species Cross-reactivity:
- Applications:
- Isotype:
-
Brand:
CAT.NO. : ARA6518
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Size:
Trail, Bulk size or Custom requests Please contact us
Product Details
Background
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGFalpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG, and HBEGF/heparin-binding EGF. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase AKT, PLCgamma-PKC, and STATs modules. May also activate the NF-kappa-B signaling cascade. Plays a role in enhancing learning and memory performance.
Application
|
Application |
Dilution Ratio |
|
WB |
1:5,000-1:10,000 |
|
IHC-P |
1:100-1:200 |
|
IF/ICC |
1:200-1:800 |
|
FC |
1:50-1:200 |
|
IP |
1:5-1:10 |
Overview
|
Host Species |
Rabbit |
|
Species Cross-reactivity |
Human, Mouse, Rat |
|
Application |
WB, IHC-P, IF/ICC, FC, IP |
|
Immunogen |
A synthetic peptide corresponding to EGFR residues within the aa1000-1100 (intracellular) of human EGFR. |
|
Purity |
ProA affinity purified IgG |
|
Clone Type |
Recombinant Monoclonal |
|
Isotype |
IgG |
|
Buffer |
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05% |
Storage
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Note
For Research Use Only. Not for use in diagnostic procedures.
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