SALL4 Mouse Monoclonal Antibody(ARA642)

Datasheet

MSDS

Key features and details

Target: SALL4
Clone ID: ARA642
Source/Host: Mouse
Reactivity: Human
Clonality: Monoclonal
Application: IHC
Dilution: 1:500-1:1000
Storage: -20°C

Brand:

CAT.NO. : ARA6346

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Size:

1mL

Trail, Bulk size or Custom requests Please contact us

Product Details

Background

Sal-like protein 4 (SALL4) is a transcription factor encoded by a member of the Spalt-like (SALL) gene family, SALL4. The SALL genes were identified based on their sequence homology to Spalt, which is a homeotic gene originally cloned in Drosophila melanogaster that is important for terminal trunk structure formation in embryogenesis and imaginal disc development in the larval stages. There are four human SALL proteins (SALL1, 2, 3, and 4) with structural homology and playing diverse roles in embryonic development, kidney function, and cancer. The SALL4 gene encodes at least three isoforms, termed A, B, and C, through alternative splicing, with the A and B forms being the most studied. SALL4 can alter gene expression changes through its interaction with many co-factors and epigenetic complexes. It is also known as a key embryonic stem cell (ESC) factor.

Application

To ensure optimal assay performance, AREX recommends conducting reagent titration tailored to each testing system for optimal detection results.

Application	Dilution Ratio
IHC	1:500-1:1000

*Results are sample-specific. Please refer to your local assay conditions and test parameters for reference.

Overview

Antibody Type	Primary antibodies
Isotype	IgG1
Positive Control	NCCIT cell lysates, human seminoma tissue, human embryonal carcinoma tissue, human testis tissue, NCCIT.
Localization	Cytoplasm, Nucleus.
Form/Buffer	PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Purification	Protein A affinity purified.
Alternative Names	AA407717 antibody; AL022809 antibody; AW536104 antibody; C330011P20Rik antibody; C78083 antibody; C78563 antibody; dJ1112F19.1 antibody; DRRS antibody; HSAL4 antibody; Sal like 4 (Drosophila) antibody; Sal like 4 antibody; Sal like Protein 4 antibody; Sal-like protein 4 antibody; Sall4 antibody; SALL4_HUMAN antibody; Spalt like transcription factor 4 antibody; Tex20 antibody; Zinc finger protein 797 antibody; Zinc finger protein SALL4 antibody; ZNF797 antibody
Molecular Weight	Predicted band size: 112 kDa
Imnunogen	Recombinant protein within human SALL4 aa 904-1,053/1,053.
UniProt	Q9UJQ4(Human);

*AREX continuously optimizes our products. Webpage content may not reflect the latest updates. For inquiries, please contact info@arexbio.com or your local distributor.
*Clone Number, Reactivity, Source/Host and Clonality can be found in the product name and Key Features section above.

Data

Immunohistochemical analysis of paraffin-embedded human embryonal carcinoma tissue with SALL4 Mouse Monoclonal Antibody(ARA642) .

Immunohistochemical analysis of paraffin-embedded human testis tissue with SALL4 Mouse Monoclonal Antibody(ARA642).

Storage

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

Note

For Research Use Only. Not for diagnostic, therapeutics, prophylactic or in vivo use.

FAQs

Are the pathology antibodies provided by AREX raw antibodies or ready-to-use solutions?

AREX Biosciences specializes in supplying high-quality IHC pathology raw antibodies (Raw Antibodies). We do not manufacture ready-to-use working solutions or IVD diagnostic reagents. We mainly provide concentrated raw materials to pathology reagent manufacturers and diagnostic platform companies to support product development and OEM production.

What development scenarios are pathology raw antibodies mainly used for?

Our raw antibodies are primarily used for the research, performance optimization, validation, and commercial-scale production of pathology IHC detection reagents. They are also suitable for companion diagnostics (CDx) projects and antibody screening.

How can I evaluate whether a raw antibody is suitable for our staining platform?

It is recommended to focus on specificity, sensitivity, background control, and performance on your target automated platforms (such as Roche Ventana, Leica Bond, Agilent Dako, etc.). We can provide internal test data for reference, but we recommend partners perform actual validation on their own platforms.

Can you provide samples for platform validation?

Yes. We can provide validation samples depending on the specific product. Some products may be provided free of charge, while others may involve a small sample fee. Handling fee and shipping fee will be charged separately. Please contact us for detailed confirmation.

How should raw antibodies be paired with detection systems?

AREX raw antibodies can be used with various polymer detection systems and ancillary reagents. We recommend optimization in combination with the ARExVisual® system or your existing detection platform to achieve better signal intensity and background control.

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