p53 Rabbit Monoclonal Antibody(ARA752)

Key features and details

  • Target: p53
  • Clone ID: ARA752
  • Host: Rabbit
  • Clone Type: Recombinant Monoclonal
  • Purity: ProA affinity purified IgG
  • Species Cross-reactivity: Human
  • Applications: WB, IHC-P, IF/ICC, FC
  • Isotype: IgG
  • Brand:
CAT.NO. : ARA6539
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Size:
Trail, Bulk size or Custom requests Please contact us
Product Details
Background
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis; the function is largely independent of transcription.
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