ISCU Rabbit Polyclonal Antibody
CAT.NO. : ARA6895
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Size:
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Background
Iron-sulfur (Fe-S) clusters are necessary for several mitochondrial enzymes and other subcellular compartment proteins. They contain sulfur and iron, and are created via several steps that include cysteine desulfurases, iron donors, chaperones, and scaffold proteins. This gene encodes the two isomeric forms, ISCU1 and ISCU2, of the Fe-S cluster scaffold protein. Mutations in this gene have been found in patients with myopathy with severe exercise intolerance and myoglobinuria.
Application
|
Application |
Dilution Ratio |
|
WB |
1:500 - 1:2000 |
Overview
|
Product Description |
Rabbit polyclonal antibody to ISCU |
|
Immunogen |
Recombinant fusion protein of human ISCU. The exact sequence is proprietary. |
|
Purification Method |
The antibody was purified by immunogen affinity chromatography. |
|
Clone Type |
Polyclonal |
|
Product Form |
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide. |
|
Gene Name |
ISCU |
|
Alternative Names |
NIFUN; Iron-sulfur cluster assembly enzyme ISCU mitochondrial; NIFU-like N-terminal domain-containing protein; NIFU-like protein |
|
Gene ID (Human) |
23479; |
|
Gene ID (Mouse) |
66333; |
|
Protein ID (Human) |
Q9H1K1; |
|
Protein ID (Mouse) |
Q9D7P6; |
Data
-
Western blot analysis of ISCU expression in HEK293T (A), A549 (B) whole cell lysates. (Predicted band size: 17 kD; Observed band size: 25 kD)
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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