CD79a Rabbit Monoclonal Antibody(ARA771)

Key features and details

  • Target: CD79a
  • Clone ID: ARA771
  • Host: Rabbit
  • Clone Type: Recombinant Monoclonal
  • Purity: ProA affinity purified IgG
  • Species Cross-reactivity: Human
  • Applications: WB, IHC-P, FC
  • Isotype: IgG
  • Brand:
CAT.NO. : ARA6558
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Size:
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Product Details
Background
Required in cooperation with CD79b for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate.
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