Caspase-9(pro+p35) Rabbit Monoclonal Antibody(ARA813)
Key features and details
- Target:
- Clone ID:
- Host:
- Clone Type:
- Purity:
- Species Cross-reactivity:
- Applications:
- Isotype:
-
Brand:
CAT.NO. : ARA6600
US$ Please choose
US$ Please choose
Size:
Trail, Bulk size or Custom requests Please contact us
Product Details
Background
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in an ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose)polymerase (PARP). Isoform 2 lacks activity and is a dominant-negative inhibitor of caspase-9.
New Products
