CD3 Rabbit Monoclonal Antibody(ARA817)
Key features and details
- Target:
- Clone ID:
- Host:
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- Purity:
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Brand:
CAT.NO. : ARA6607
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Product Details
Background
The CD3 protein is a T-cell marker, a complex of four structurally distinct membrane glycoprotein isoforms, 20-50kDa, comprising extracellular, transmembrane and intracellular domains. The CD3 complex is responsible for mediating signal transduction to the internal environment upon antigenic recognition by TCR, causing T-cell proliferation and release of cytokines. Except for a weak expression in Purkinje cells (with some of the Abs) and activated NK-cells, CD3 is found only in T-cells.
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