Uroplakin 1b(UPK1B) Rabbit Monoclonal Antibody(ARB576)
Key features and details
- Reactivity:Human
- Application:IHC
- Host:Rabbit
- Clonality:Monoclonal
- Target:Uroplakin 1b(UPK1B)
-
Brand:
CAT.NO. : ARB6868
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Size:
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Product Details
Background
Uroplakin 1b (UPK1B) is one out of 5 known uroplakin protein particles that cooperatively form apical asymmetric unit membrane (AUM) plaques which play an important role in the stabilization and strengthening of epithelial cells that line the bladder. UPK1B is expressed in a limited number of normal tissues, including the bladder, stomach and tonsils. The significant advantage of moderate to strong membrane UPK1B immunostaining in urothelial carcinoma indicates that positive UPK1B staining has high specificity in distinguishing urothelial carcinoma form other tumors.
Application
|
Application |
Dilution Ratio |
|
IHC-P |
1:100-1:200 |
Overview
|
Predicted Molecular Wt |
30kDa |
|
Species Cross-reactivity |
Human |
|
Applications |
IHC-P |
|
Purity |
ProA affinity purified IgG |
|
Form |
Liquid |
|
SwissProt ID |
O75841 |
|
Subcellular location |
Cytoplasm and membrane |
|
Recommended Method |
Heat induced epitope retrieval with Tris-EDTA buffer (pH 9.0), primary antibody incubate at RT (18℃-25℃) for 30 minutes. |
|
Immunogen |
Synthetic peptide. |
|
Storage Buffer |
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05% |
Data
Immunohistochemical staining of urothelial carcinoma using Uroplakin 1b(UPK1B) Rabbit Monoclonal Antibody(ARB576)
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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