Human KIM-1 ELISA Kit
Key features and details
- Sensitivity:15 pg/ml
- Detection Range:31.2 pg/ml - 2000 pg/ml
- Sample Types: Cell Culture Supernates, Serum, Plasma, Cell Lysates, Urine
- Species:Human
- Detection Method: Colorimetric
- Target:KIM-1
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Brand:
CAT.NO. : ARE6640
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Size:
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Product Details
Background
CD365 also known as T-cell immunoglobulin and mucin domain 1 (Tim-1) is a type 1 surface glycoprotein that consists of extracellular N-terminal immunoglobulin V-like domain and a mucin domain, and a short cytoplasmic tail. The endogenous ligand for CD365 is Tim-4. In addition, CD365 is known to be a cellular receptor or co-receptor for a number of viruses including hepatitis A and C viruses, Ebola virus, Marburg virus, Dengue virus, Zika virus, West Nile virus, and Japanese encephalitis virus. The direct binding of the viruses by CD365 occurs via phosphatildyl-serine exposed on viral envelopes. Polymorphisms within human CD365 gene (HAVCR1) are associated with susceptibility to infection and the disease severity. CD365 has also been implicated in the T cell co-stimulation. CD365 is primarily expressed in epithelial cells. It is also highly expressed in A549, 769-P and Caco-2 and cell lines. CD365 exists also as a soluble protein generated by metalloproteinase mediated proteolytic cleavage of the surface protein.
Overview
|
Product Description |
Sandwich ELISA for quantitative detection of Human KIM-1 concentrations. |
|
Sensitivity |
15 pg/ml |
|
Assay Method |
Colorimetric |
|
Assay Range |
31.2 pg/ml - 2000 pg/ml |
|
Gene Symbol |
HAVCR1 |
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Alternative Names |
KIM1; TIM1; TIMD1; Hepatitis A virus cellular receptor 1; HAVcr-1; Kidney injury molecule 1; KIM-1; T-cell immunoglobulin and mucin domain-containing protein 1; TIMD-1; T-cell immunoglobulin mucin receptor 1; TIM; TIM-1; T-cell membrane protein 1 |
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Gene ID (Human) |
26762 |
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Protein ID (Human) |
Q96D42 |
Data
Standard Curve
Storage
Shipped and store at 4°C, don't cryopreserve.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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