CDK4 Rabbit Monoclonal Antibody(ARA778)

Key features and details

  • Target: CDK4
  • Clone ID: ARA778
  • Host: Rabbit
  • Clone Type: Recombinant Monoclonal
  • Purity: ProA affinity purified IgG
  • Species Cross-reactivity: Human Mouse
  • Applications: WB, IF/ICC, FC, IP
  • Isotype: IgG
  • Brand:
CAT.NO. : ARA6565
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Size:
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Product Details
Background
Cyclin-dependent kinase-4 (CDK4) is a protein-serine kinase involved in the cell cycle. It is essential for the G1-to S-phase transition during the cell cycle and its expression is primarily controlled at the transcriptional level. CCND1-CDK4 axis is not only critical in glial tumor cells but also in stromal-derived cells in the surrounding tumor microenvironment that are vital to sustain tumor outgrowth.
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