CD138 Mouse Monoclonal Antibody(ARM874)
Hoja de datos
Key features and details
- Objetivo:
- Identificación del clon:
- Fuente/Anfitrión:
- Reactividad:
- Aplicaciones:
- Dilución:
- Clonalidad:
- Almacenamiento:
-
Marca:
CAT.NO. : ARM6664
US$ Please choose
US$ Please choose
Tamaño:
Trail, Bulk size or Custom requests Please contact us
Product Details
Antecedentes
Cluster of Differentiation 138 (CD138), also known as Syndecan-1, is a trans- membrane glycoprotein present on the surface of B-cells during late stage differentiation. Anti-CD138 is used to differentiate marginal zone lymphoma from lymphoplasmacytic lymphoma. ALK+ Large B-Cell Lymphoma (LBCL) commonly stains positively for CD138, but not for CD20 and CD79a. Anti-CD138 reacts positively with HHV8-associated primary effusion lymphoma that lacks B-cell markers. CD138 is also a useful marker for identifying and enumerating benign, reactive, or malignant plasma cells from the bone marrow biopsy samples.
Solicitud
To ensure optimal assay performance, AREX recommends conducting reagent titration tailored to each testing system for optimal detection results.
*Results are sample-specific. Please refer to your local assay conditions and test parameters for reference.
Solicitud | IHC |
Dilution Ratio | 1:50 - 1:200 |
Descripción general
Tipo de anticuerpo | Primary antibodies |
isotipo | IgG1 |
Positive Control | Amígdala |
Localización | membranoso |
Formulario/búfer | Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide |
Purificación | Purificado |
Conjugación | Sin conjugar |
Alternative Names | SDC; Syndecan-1; SYND1; CD138 |
Símbolo genético | COSUDE1 |
Entrez Gene | 6382 |
Uniprot | P18827 |
*Clone Number, Reactivity, Source/Host and Clonality can be found in the product name and Key Features section above.
Datos
Immunohistochemical staining of human tonsil tissue using CD138 Mouse Monoclonal Antibody (ARM874)
Almacenamiento
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for diagnostic, therapeutics, prophylactic or in vivo use.
Preguntas frecuentes
Are the pathology antibodies provided by AREX raw antibodies or ready-to-use solutions?
AREX Biosciences specializes in supplying high-quality IHC pathology raw antibodies (Raw Antibodies). We do not manufacture ready-to-use working solutions or IVD diagnostic reagents. We mainly provide concentrated raw materials to pathology reagent manufacturers and diagnostic platform companies to support product development and OEM production.
What development scenarios are pathology raw antibodies mainly used for?
Our raw antibodies are primarily used for the research, performance optimization, validation, and commercial-scale production of pathology IHC detection reagents. They are also suitable for companion diagnostics (CDx) projects and antibody screening.
How can I evaluate whether a raw antibody is suitable for our staining platform?
It is recommended to focus on specificity, sensitivity, background control, and performance on your target automated platforms (such as Roche Ventana, Leica Bond, Agilent Dako, etc.). We can provide internal test data for reference, but we recommend partners perform actual validation on their own platforms.
Can you provide samples for platform validation?
Yes. We can provide validation samples depending on the specific product. Some products may be provided free of charge, while others may involve a small sample fee. Handling fee and shipping fee will be charged separately. Please contact us for detailed confirmation.
How should raw antibodies be paired with detection systems?
AREX raw antibodies can be used with various polymer detection systems and ancillary reagents. We recommend optimization in combination with the ARExVisual® system or your existing detection platform to achieve better signal intensity and background control.
Nuevos productos
