CPA1/Carboxypeptidase 1 Rabbit Monoclonal Antibody(ARA649)

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CPA1/Carboxypeptidase 1 Rabbit Monoclonal Antibody(ARA649)

Key features and details

Target: CPA1/Carboxypeptidase 1
Host: Rabbit
Reactivity: Human
Clonality: Monoclonal
Applications: IHC
Conjugation: Unconjugated
Storage: -20°C

Brand:

CAT.NO. : ARA6356

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Size:

1mL

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Product Details

Background

Carboxypeptidase A1 is an enzyme that in humans is encoded by the CPA1 gene. Three different forms of human pancreatic procarboxypeptidase A have been isolated. The A1 and A2 forms are monomeric proteins with different biochemical properties. Carboxypeptidase A1 is a monomeric pancreatic exopeptidase. It is involved in zymogen inhibition. Carboxypeptidase B (EC 3.4.17.2, protaminase, pancreatic carboxypeptidase B, tissue carboxypeptidase B, peptidyl-L-lysine [L-arginine]hydrolase) is a carboxypeptidase that preferentially cleaves off basic amino acids arginine and lysine from the C-terminus of a peptide. This enzyme is secreted by the pancreas, and it travels to the small intestine, where it aids in protein digestion. Plasma carboxypeptidase B (carboxypeptidase B2) is responsible for converting the C5a protein into C5a des-Arg, with one less amino acid.

Application

Application	Dilution Ratio
IHC	1:50 - 1:200

Overview

Antibody Type	Recombinant Rabbit monoclonal Antibody
Immunogen	Recombinant protein within Human Carboxypeptidase A1 aa 320-419 / 419.
Predicted Molecular Weight	47 kDa
Positive Control	Mouse pancreas tissue lysate, rat pancreas tissue lysate, human pancreas tissue, mouse pancreas tissue, rat pancreas tissue.
Form	Liquid
Storage Buffer	1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Isotype	IgG
Purification Method	Protein A affinity purified.
Uniprot ID	P15085 (Human), P48052 (Human), P15086 (Human), Q7TPZ8 (Mouse), P00731 (Rat), P19222 (Rat), P19223 (Rat)
Alternative Names	carboxypeptidase A1 (pancreatic), Carboxypeptidase A1, Carboxypeptidase A1 precursor, CBPA1_HUMAN, CPA, CPA1, Pancreatic carboxypeptidase A1, Procarboxypeptidase A1 pancreatic, Carboxypeptidase A2, CPA2, Carboxypeptidase B, Carboxypeptidase B1 (tissue), Carboxypeptidase B1, CarboxypeptidaseB, CarboxypeptidaseB1, CBPB1_HUMAN, CP B1, CPB 1, CPB, CPB1, DKFZp779K1333, Pancreas specific protein, Pancreas-specific protein, Pancreatic carboxypeptidase B, Pancreatic carboxypeptidase B1, PASP, PCPB, Procarboxypeptidase B, Procarboxypeptidase B pancreatic, Protaminase, Tissue carboxypeptidase B

Data

Immunohistochemical analysis of paraffin-embedded human pancreas tissue with CPA1/Carboxypeptidase 1 Rabbit Monoclonal Antibody(ARA649) at 1/1,000 dilution.

Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Note

For Research Use Only. Not for use in diagnostic procedures.

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